The part of the brain that regulates body temperature is the hypothalamus. This small region located at the base of the brain plays a crucial role in maintaining the body’s internal environment through homeostasis. It detects changes in blood temperature and initiates appropriate responses such as sweating, shivering, or altering blood flow to maintain a stable core temperature. The hypothalamus integrates various inputs from the body, ensuring that temperature regulation is effective across various physiological processes.