The primary challenge of managing wildlife in the Anthropocene is addressing habitat fragmentation and human-induced pressures. Rapid urbanization, land use change, and climate change create fragmented landscapes that hinder wildlife migration and reduce biodiversity. Conservation strategies often struggle to balance human development with ecological needs, leading to conflicts over land use and resource allocation. Additionally, invasive species and pollution further complicate management efforts. Effective wildlife management in this era necessitates innovative approaches that integrate ecological science, community engagement, and policy advocacy to ensure sustainable coexistence.