The process by which substances are absorbed through the skin is known as transdermal absorption. This method allows certain compounds, such as medications or cosmetic ingredients, to enter the bloodstream through the epidermis. The effectiveness of transdermal absorption depends on factors like molecular size, lipophilicity, and the condition of the skin. This technique is often utilized in drug delivery systems, enabling a steady release of medication over time, enhancing therapeutic efficacy while minimizing side effects.