The first woman to hold a cabinet position in the United States was Frances Perkins, who served as Secretary of Labor from 1933 to 1945. Appointed by President Franklin D. Roosevelt, Perkins was pivotal in shaping labor policies during the New Deal era. Her tenure focused on improving workers' rights, establishing social security, and enhancing labor laws. Perkins’ appointment marked a significant milestone in U.S. history, showcasing women's growing involvement in government and public policy.