The significance of the Berlin Wall in global politics lies in its symbolism as a divide between communism and democracy during the Cold War. Constructed in 1961, it physically represented the ideological struggle between the Eastern Bloc and the Western powers. Its fall in 1989 marked a pivotal moment, symbolizing the end of communist control in Eastern Europe, the reunification of Germany, and a shift toward democratization and the expansion of Western influence across the continent, impacting global relationships.