The significance of the U.S. Bill of Rights lies in its role as a foundational document that guarantees individual liberties and protections against government overreach. Ratified in 1791, the Bill encompasses the first ten amendments to the Constitution, securing essential rights such as freedom of speech, religion, and assembly. This framework establishes the principle of limited government, ensuring that citizens' rights are safeguarded. The Bill of Rights serves as a critical benchmark for evaluating the protection of civil liberties and has influenced numerous legal cases and societal norms.