The Tenth Amendment to the U.S. Constitution emphasizes the principle of federalism by stating that powers not delegated to the federal government are reserved for the states or the people. This amendment reinforces the limitations on federal authority and advocates for the autonomy of state governments. By guaranteeing states the authority to legislate on a range of issues, the Tenth Amendment plays a critical role in balancing power and protecting state rights, which can lead to differing laws and policies across the country.