The famous artist known for his works during the High Renaissance in Italy is Leonardo da Vinci. Renowned for his exceptional talent in painting, sculpture, and science, da Vinci produced iconic masterpieces such as the Mona Lisa and The Last Supper. His innovative techniques, including the use of sfumato and detailed anatomical studies, set new standards in the art world. Da Vinci's diverse interests encompassed not only art but also engineering and anatomy, embodying the Renaissance ideal of the polymath. His contributions significantly impacted the course of art history and the understanding of human anatomy.