The ancient Egyptian queen known for her political alliances and influence was Cleopatra VII. As the last active ruler of the Ptolemaic Kingdom, she is famous for her relationships with powerful Roman leaders, including Julius Caesar and Mark Antony. Cleopatra's skill in diplomacy and her ability to speak multiple languages enhanced her political standing, allowing her to navigate a tumultuous period in Egyptian history. Her reign marked significant political and cultural interactions between Egypt and Rome, ultimately culminating in a larger narrative of the decline of Egyptian power during the Roman conquest.