The significance of the 1776 Declaration of Independence lies in its articulation of the colonies' reasons for seeking independence from Britain. Drafted primarily by Thomas Jefferson, the Declaration asserted the inherent rights of individuals, including life, liberty, and the pursuit of happiness, and established the principle that government derives its power from the consent of the governed. This document not only united the thirteen colonies in their struggle for freedom but also laid the ideological foundation for democratic principles and inspired future movements for independence and human rights worldwide.