The Great Plague of 1665 had a profound impact on England's population, leading to the deaths of an estimated 100,000 people in London alone, about 15% of the city's population at the time. This epidemic disrupted daily life, causing fear, social upheaval, and a breakdown in community structures as families were decimated and many fled the cities. The resulting labor shortage and demographic shifts impacted the economy, contributing to the decline of feudalism and possibly accelerating the move toward a more modern labor market. The societal implications prompted changes in public health measures and attitudes towards disease that would influence future responses to health crises.