The cultural significance of the Renaissance in Europe was profound, as it marked a rebirth of interest in art, science, and the classical knowledge of ancient Greece and Rome. Spanning from the 14th to the 17th century, the Renaissance celebrated humanism, emphasizing individual potential and critical thinking. This period saw the flourishing of arts, with figures like Leonardo da Vinci and Michelangelo producing masterpieces that continue to influence culture today. Additionally, advancements in science and technology, such as those made by Copernicus and Galileo, challenged traditional beliefs, laying the groundwork for the modern scientific approach and reshaping European thought.