The major rebellion aimed at ending British rule in the American colonies was the American Revolution, which lasted from 1775 to 1783. This uprising stemmed from escalating tensions between the colonies and Britain, fueled by perceived injustices such as taxation without representation. The rebellion involved various acts of defiance, including the Boston Tea Party and the First Continental Congress. Key figures, including George Washington and Thomas Jefferson, emerged as leaders advocating for independence. Ultimately, the successful outcome of the revolution established the United States as an independent nation, marking a significant milestone in the struggle for self-determination and democratic governance.