Creatine supplementation plays a significant role in strength training by enhancing ATP production, which fuels high-intensity exercise. This can lead to increased power output and improved muscle endurance. Creatine helps in quicker recovery between sets, allowing athletes to maximize their training sessions. Additionally, it can contribute to muscle hypertrophy by enhancing cell volumization and promoting favorable hormonal responses. Overall, creatine is a well-researched supplement that can effectively enhance strength and athletic performance.