The largest desert in both North and South America is the Patagonian Desert. Located primarily in Argentina, this cold desert spans approximately 620,000 square miles, making it one of the largest deserts globally. Characterized by its arid climate and unique Patagonian landscape, the desert features distinct vegetation, including shrubs and grasses adapted to harsh conditions. The Patagonian Desert is also renowned for its stunning geological formations, diverse wildlife, and significant climatic influences stemming from the Andes mountain range.