The city best known for its nightlife and vibrant art scene in Spain is Barcelona. Famous for its lively streets, including Las Ramblas, and eclectic neighborhoods like Gothic Quarter, Barcelona offers a rich cultural experience. The city is home to numerous art galleries, theaters, and live music venues, making it a hub for artistic expression. Additionally, Barcelona’s nightlife is vibrant, with countless bars, clubs, and restaurants that attract both locals and tourists. Its unique blend of culture and entertainment makes it a must-visit destination.