The major river that flows through Paris, France, is the Seine River. This iconic river is approximately 777 kilometers long and plays a vital role in the city's history and development. The Seine is lined with famous landmarks, including the Eiffel Tower and the Louvre Museum, making it a popular destination for tourists. The river also serves as a significant transportation route and has been essential for commerce since ancient times. Boat cruises on the Seine offer unique views of Paris's stunning architecture.