The largest geographical region in the U.S. by area is Alaska. With over 663,000 square miles, Alaska is known for its vast wilderness, including forests, mountains, and coastlines. It is significantly larger than any other state, accounting for about 18% of the total U.S. land area. Alaska has a diverse ecosystem, rich in natural resources like oil, gas, and minerals. Its stunning landscapes and unique wildlife attract tourists and outdoor enthusiasts, while its Indigenous cultures are a vital part of its historical heritage.