The novel that begins with the line "It was the best of times, it was the worst of times" is "A Tale of Two Cities," written by Charles Dickens and published in 1859. The story is set in London and Paris before and during the French Revolution, exploring themes of resurrection, sacrifice, and the struggles between social classes. This opening line highlights the stark contrasts of the era, embodying the duality of society during tumultuous times. Dickens’ narrative deftly weaves personal stories with historical events, making it one of his most famous works and a classic of English literature.