The human organ primarily responsible for detoxification is the liver. The liver is a vital organ that performs a wide range of functions crucial for maintaining metabolic processes and overall health. It detoxifies various metabolites, processes nutrients absorbed from the digestive tract, and produces bile to aid digestion. The liver also plays a key role in regulating blood sugar levels, cholesterol production, and the synthesis of proteins essential for blood clotting. Its ability to regenerate after damage makes it unique. A healthy liver is crucial for overall bodily functions and the prevention of various diseases.