The organ in the human body primarily responsible for detoxifying chemicals is the liver. This vital organ plays a crucial role in metabolizing substances, processing nutrients, and removing toxins from the bloodstream. The liver filters toxins and waste products, breaking them down and facilitating their elimination through urine or bile. Additionally, it stores essential nutrients, such as vitamins and minerals, while helping regulate blood sugar levels and cholesterol. The liver's ability to regenerate allows it to recover from damage, although excessive alcohol consumption or certain diseases can impair its function. Maintaining liver health is essential for overall well-being.