The major ocean that separates Africa from North America is the Atlantic Ocean. It is the second-largest ocean in the world and plays a significant role in global trade and climate. The Atlantic Ocean features several important shipping routes and is home to the Bermuda Triangle, a region renowned for unexplained disappearances of ships and aircraft. Additionally, the Atlantic Ocean has diverse marine ecosystems that support various species of fish and other marine life, making it crucial for both environmental and economic reasons.