The main ingredient in chili con carne is typically ground beef. This hearty dish combines the richness of beef with spices, beans, tomatoes, and other flavorings to create a savory stew. While variations exist—some may include pork, turkey, or even vegetarian substitutes—the beef version is the most traditional and well-known. The blend of spices, such as chili powder and cumin, enhances the dish’s flavor profile, making it a popular choice in many cuisines, especially in Tex-Mex cooking.