The main component of the human skeleton is collagen, a type of protein that provides structural support and strength. Collagen fibers form a framework for bones, helping to maintain their shape and cohesiveness. The skeleton is also composed of minerals, mainly calcium and phosphorus, which provide rigidity and hardness to the bones. Alongside collagen, other proteins and minerals contribute to the overall structure, but collagen is by far the most significant component, constituting about 30% of the total bone mass in humans.