The largest breed of dog is the Great Dane. Known for its towering height and gentle temperament, a fully grown Great Dane can stand between 28 to 34 inches at the shoulder, with some individuals exceeding this range. Despite their imposing size, they are often referred to as "gentle giants" due to their friendly and affectionate nature. Great Danes are known for their loyalty and are excellent family pets, although they do require proper training and socialization. Their sheer size and presence make them both majestic and iconic within the canine world.