The famous artist who painted the Mona Lisa is Leonardo da Vinci. This iconic portrait, characterized by its enigmatic expression and innovative use of sfumato, was created during the Italian Renaissance. The painting's allure lies not only in its exquisite artistry but also in the mystery surrounding the subject's identity and the painting's history. The Mona Lisa has become perhaps the most recognizable painting in the world, representing a pinnacle of artistic achievement and cultural significance throughout the centuries.